3fc1

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File:3fc1.jpg

Template:STRUCTURE 3fc1

Crystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitorCrystal structure of p38 kinase bound to pyrimido-pyridazinone inhibitor

Template:ABSTRACT PUBMED 16302819

About this StructureAbout this Structure

3FC1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Evaluating the molecular mechanics poisson-boltzmann surface area free energy method using a congeneric series of ligands to p38 MAP kinase., Pearlman DA, J Med Chem. 2005 Dec 1;48(24):7796-807. PMID:16302819

Are free energy calculations useful in practice? A comparison with rapid scoring functions for the p38 MAP kinase protein system., Pearlman DA, Charifson PS, J Med Chem. 2001 Oct 11;44(21):3417-23. PMID:11585447

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