Transcription Termination Factor Rho

Transcription termination factor Rho is a ring-shaped RNA-DNA helicase that induces release of transcription complexes at specific locci of bacterial genomes. Several structures of Rho in various liganted states haven been solved by X-ray cristallography by the Berger lab (Berkeley). Here is one representation showing the Rho hexamer in a closed state and with RNA fragments occupying both its primary and secondary binding sites. <applet load='Rho1.pdb' size='300' frame='true' align='right' caption='Insert caption here' / <scene name='Transcription_Termination_Factor_Rho/Rho_closed_1/2'>TextToBeDisplayed</scene>