1u1s
Hfq protein from Pseudomonas aeruginosa. Low-salt crystals
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OverviewOverview
The structure of the Hfq protein from Pseudomonas aeruginosa was, determined using two different ionic conditions. In both cases the, molecules formed identical hexameric rings, but some variations in the, crystal packing were revealed. Hfq belongs to the family of Sm/LSm, proteins, the members of which can form hexameric as well as heptameric, rings. Comparative analysis of known structures of this protein family, shows that the fragment of the Sm-fold responsible for oligomerization is, strongly structurally conserved. In the heptameric ring, three conserved, hydrogen bonds between beta-strands of adjacent molecules hold together, the monomers, whereas in the hexameric rings of Hfq an additional, conserved inaccessible hydrogen bond between neighbouring monomers is, observed.
About this StructureAbout this Structure
1U1S is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
ReferenceReference
Structure of Pseudomonas aeruginosa Hfq protein., Nikulin A, Stolboushkina E, Perederina A, Vassilieva I, Blaesi U, Moll I, Kachalova G, Yokoyama S, Vassylyev D, Garber M, Nikonov S, Acta Crystallogr D Biol Crystallogr. 2005 Feb;61(Pt 2):141-6. Epub 2005, Jan 19. PMID:15681864
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