1o43

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Template:STRUCTURE 1o43

File:1o43.png

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82129.CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU82129.

Template:ABSTRACT PUBMED 14613321

DiseaseDisease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this StructureAbout this Structure

1O43 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321

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