2dqt
High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analogHigh resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog
Template:ABSTRACT PUBMED 17428500
About this StructureAbout this Structure
This structure supersedes the now removed PDB entry 1hyx. Full crystallographic information is available from OCA.
ReferenceReference
Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis., Oda M, Ito N, Tsumuraya T, Suzuki K, Sakakura M, Fujii I, J Mol Biol. 2007 May 25;369(1):198-209. Epub 2007 Mar 15. PMID:17428500
Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization., Miyashita H, Hara T, Tanimura R, Fukuyama S, Cagnon C, Kohara A, Fujii I, J Mol Biol. 1997 Apr 18;267(5):1247-57. PMID:9150409
A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tamimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10757. PMID:7938025
A common ancestry for multiple catalytic antibodies generated against a single transition-state analog., Miyashita H, Hara T, Tanimura R, Tanaka F, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6045-9. PMID:8016113
Prodrug activation via catalytic antibodies., Miyashita H, Karaki Y, Kikuchi M, Fujii I, Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5337-40. PMID:8506382
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