2o8d

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Template:STRUCTURE 2o8d

File:2o8d.png

human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispairhuman MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair

Template:ABSTRACT PUBMED 17531815

DiseaseDisease

Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[609309], Mismatch repair cancer syndrome OMIM:[609309], Muir-Torre syndrome OMIM:[609309]

About this StructureAbout this Structure

2O8D is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:17531815

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