2r3r

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Template:STRUCTURE 2r3r

File:2r3r.png

Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitorCrystal Structure of Cyclin-Dependent Kinase 2 with inhibitor

Template:ABSTRACT PUBMED 17937404

About this StructureAbout this Structure

2R3R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structure-guided discovery of cyclin-dependent kinase inhibitors., Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V, Biopolymers. 2007 Oct 15;. PMID:17937404

Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors., Dwyer MP, Paruch K, Alvarez C, Doll RJ, Keertikar K, Duca J, Fischmann TO, Hruza A, Madison V, Lees E, Parry D, Seghezzi W, Sgambellone N, Shanahan F, Wiswell D, Guzi TJ, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6216-9. Epub 2007 Sep 8. PMID:17904366

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