2v2c
THE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIMTHE A178L MUTATION IN THE C-TERMINAL HINGE OF THE FLEXIBLE LOOP-6 OF TRIOSEPHOSPHATE ISOMERASE (TIM) INDUCES A MORE CLOSED CONFORMATION OF THIS HINGE REGION IN DIMERIC AND MONOMERIC TIM
Template:ABSTRACT PUBMED 18219118
About this StructureAbout this Structure
2V2C is a Single protein structure of sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
ReferenceReference
Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM., Alahuhta M, Casteleijn MG, Neubauer P, Wierenga RK, Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):178-88. Epub 2008, Jan 16. PMID:18219118
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OCACategories:
- Pages with broken file links
- Single protein
- Triose-phosphate isomerase
- Trypanosoma brucei brucei
- Alahuhta, M.
- Casteleijn, M G.
- Neubauer, P.
- Wierenga, R K.
- 2-phospho glycollate
- 2pg
- A178l
- Engineering
- Enzyme
- Fatty acid biosynthesis
- Gluconeogenesis
- Glycolysis
- Glycosome
- Hinge
- Isomerase
- Lipid synthesis
- Loop-6
- Loop6
- Pentose shunt
- Point mutation
- Tim
- Tim-barrel
- Triosephosphate isomerase