1zp5
Crystal structure of the complex between MMP-8 and a N-hydroxyurea inhibitorCrystal structure of the complex between MMP-8 and a N-hydroxyurea inhibitor
Template:ABSTRACT PUBMED 16242329
About this StructureAbout this Structure
1ZP5 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8., Campestre C, Agamennone M, Tortorella P, Preziuso S, Biasone A, Gavuzzo E, Pochetti G, Mazza F, Hiller O, Tschesche H, Consalvi V, Gallina C, Bioorg Med Chem Lett. 2006 Jan 1;16(1):20-4. Epub 2005 Oct 18. PMID:16242329
Hydroxamic acids as pharmacological agents., Muri EM, Nieto MJ, Sindelar RD, Williamson JS, Curr Med Chem. 2002 Sep;9(17):1631-53. PMID:12171558
Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor., Grams F, Crimmin M, Hinnes L, Huxley P, Pieper M, Tschesche H, Bode W, Biochemistry. 1995 Oct 31;34(43):14012-20. PMID:7577999
Biaryl ether retrohydroxamates as potent, long-lived, orally bioavailable MMP inhibitors., Michaelides MR, Dellaria JF, Gong J, Holms JH, Bouska JJ, Stacey J, Wada CK, Heyman HR, Curtin ML, Guo Y, Goodfellow CL, Elmore IB, Albert DH, Magoc TJ, Marcotte PA, Morgan DW, Davidsen SK, Bioorg Med Chem Lett. 2001 Jun 18;11(12):1553-6. PMID:11412979
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