1bz6

Revision as of 12:55, 20 November 2007 by OCA (talk | contribs) (New page: left|200px<br /><applet load="1bz6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bz6, resolution 1.2Å" /> '''ATOMIC RESOLUTION CRY...)
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ATOMIC RESOLUTION CRYSTAL STRUCTURE AQUOMET-MYOGLOBIN FROM SPERM WHALE AT ROOM TEMPERATURE

File:1bz6.gif


1bz6, resolution 1.2Å

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OverviewOverview

The crystal structures of myoglobin in the deoxy- and carbon, monoxide-ligated states at a resolution of 1.15 angstroms show that carbon, monoxide binding at ambient temperatures requires concerted motions of the, heme, the iron, and helices E and F for relief of steric inhibition. These, steps constitute the main mechanism by which heme proteins lower the, affinity of the heme group for the toxic ligand carbon monoxide.

About this StructureAbout this Structure

1BZ6 is a Single protein structure of sequence from Physeter catodon with SO4 and HEM as ligands. Full crystallographic information is available from OCA.

ReferenceReference

A steric mechanism for inhibition of CO binding to heme proteins., Kachalova GS, Popov AN, Bartunik HD, Science. 1999 Apr 16;284(5413):473-6. PMID:10205052

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