1b8x

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Revision as of 12:20, 20 November 2007 by OCA (talk | contribs) (New page: left|200px<br /><applet load="1b8x" size="450" color="white" frame="true" align="right" spinBox="true" caption="1b8x, resolution 2.70Å" /> '''GLUTATHIONE S-TRANSF...)
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File:1b8x.gif


1b8x, resolution 2.70Å

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GLUTATHIONE S-TRANSFERASE FUSED WITH THE NUCLEAR MATRIX TARGETING SIGNAL OF THE TRANSCRIPTION FACTOR AML-1

OverviewOverview

A glutathione S-transferase fused with the nuclear matrix targeting signal, (GST-NMTS) of AML-1/CBF-alpha2 has been crystallized by the vapor, diffusion method using polyethylene glycol (PEG) as the precipitant. The, NMTS is a 31-amino-acid signal peptide that can target the, AML-1/CBF-alpha2 protein to the nuclear matrix. The crystal belongs to, tetragonal space group P43212 with unit cell dimensions a = b = 93.4 A, c, = 57.6 A. There is one GST-fusion protein per asymmetric unit. Crystals, diffracted to at least 2.7 A and are appropriate for structure, determination.

About this StructureAbout this Structure

1B8X is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

ReferenceReference

Preliminary crystallographic study of glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor AML-1/CBF-alpha2., Tang L, Guo B, van Wijnen AJ, Lian JB, Stein JL, Stein GS, Zhou GW, J Struct Biol. 1998 Sep;123(1):83-5. PMID:9774548

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