1fka
STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION
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OverviewOverview
The small ribosomal subunit performs the decoding of genetic information, during translation. The structure of that from Thermus thermophilus shows, that the decoding center, which positions mRNA and three tRNAs, is, constructed entirely of RNA. The entrance to the mRNA channel will, encircle the message when a latch-like contact closes and contributes to, processivity and fidelity. Extended RNA helical elements that run, longitudinally through the body transmit structural changes, correlating, events at the particle's far end with the cycle of mRNA translocation at, the decoding region. 96% of the nucleotides were traced and the main fold, of all proteins was determined. The latter are either peripheral or appear, to serve as linkers. Some may assist the directionality of translocation.
About this StructureAbout this Structure
1FKA is a Protein complex structure of sequences from Thermus thermophilus with WO2 as ligand. The following page contains interesting information on the relation of 1FKA with [Ribosome]. Full crystallographic information is available from OCA.
ReferenceReference
Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution., Schluenzen F, Tocilj A, Zarivach R, Harms J, Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I, Franceschi F, Yonath A, Cell. 2000 Sep 1;102(5):615-23. PMID:11007480
Page seeded by OCA on Sun Nov 18 09:00:16 2007