2qtw
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The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain
DiseaseDisease
Known diseases associated with this structure: Hypercholesterolemia, familial, 3 OMIM:[607786]
About this StructureAbout this Structure
2QTW is a Protein complex structure of sequences from Homo sapiens with NAG and CA as ligands. Full crystallographic information is available from OCA.
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Protein complex
- Hampton, E.N.
- Harris, J.L.
- Knuth, M.W.
- Lesley, S.A.
- Li, J.
- Spraggon, G.
- CA
- NAG
- Alternative splicing
- Autocatalytic cleavage
- Calcium
- Cholesterol metabolism
- Coronary heart disease
- Disease mutation
- Glycoprotein
- Hydrolase
- Hypercholesterolemia
- Lipid metabolism
- Low density lipoprotein receptor
- Phosphorylation
- Polymorphism
- Pro-protein convertase
- Protease
- Secreted
- Serine protease
- Steroid metabolism
- Zymogen