1xud
Matrix metalloproteinase-13 complexed with non-zinc binding inhibitor
OverviewOverview
The paradigm for matrix metalloprotease inhibition combines active site tailoring and catalytic zinc ligation. But, selectivity has been difficult. Now, Engel et al. present novel compounds, completely selective for MMP-13, with a unique binding mode.
About this StructureAbout this Structure
1XUD is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
Making a new turn in matrix metalloprotease inhibition., Wasserman ZR, Chem Biol. 2005 Feb;12(2):143-4. PMID:15734640 Page seeded by OCA on Sat May 3 15:31:17 2008