7jr7

Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4

Structural highlights 7jr7 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.3Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease ABCG5_HUMAN Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. Function ABCG5_HUMAN Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. See Also ABC transporter 3D structures

spinqualitylabelsall models 7jr7, resolution 3.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image