Glycoproteins B and D

Glycoproteins B, D (gB, gD) are components of the cell-entry complex of herpes viruses. Glycoprotein D determines which cells can be infected by herpes simplex virus by binding to the cell receptors which mediate the viral entry.

spinqualitylabelsall models Herpes virus glycoprotein B trimer complex with Na+ ion (purple) (PDB entry 2gum) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of Glycoproteins B and D3D Structures of Glycoproteins B and D

Updated on 01-July-2024

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• Glycoprotein B
  • 6bm8, 5v2s – Hhv1gB – Human herpes virus 1
    
  • 6z9m – Hhv1gB – Cryo EM
    
  • 2gum, 4bom - Hhv1gB extracellular domain
    
  • 3nw8, 3nwa, 3nwd, 3nwf, 4hsi, 4l1r – Hhv1gB extracellular domain 30-730 (mutant)
    
  • 7uhz, 7ui0 – Hhv1gB + antibody – Human alphaherpesvirus 1 – Cryo EM
    
  • 6vn1 – Hhv3gB + antibody – Human alphaherpesvirus 3 – Cryo EM
    
  • 7k1s – Hhv3gB – Cryo EM
    
  • 6vlk – Hhv3gB
    
  • 7kdd – Hhv5gB + antibody – Human herpes virus 5 - Cryo EM
    
  • 6uoe – Hhv5gB + antibody
    
  • 7kdp – Hhv5gB + inhibitor – Cryo EM
    
  • 6esc, 5ys6 - ShvgB – Suid alphaherpesvirus 1
    
  • 5ys2 - ShvgB domain IV 62-148 546-700
    
  • 5zs0 - ShvgB domain IV + antibody
    
  • 4osn – hCVgB – human cytomegalovirus
    
  • 5cxf – hCVgB (mutant)
    
  • 4ot1, 5c6t – hCVgB + antibody
    
  • 6vlk – gB – varicella-zoster virus
    
  • 3fvc – EbvgB – Epstein-Barr virus
    
  • 7fbi – EbvgB + antibody - Cryo EM
    
• Glycoprotein D
  • 2c3a, 2c36, 1l2g, 4myv – Hhv1gD extracellular domain
    
  • 4myv – Hhv2gD extracellular domain - Human herpes virus 2
    
  • 5x5v – prv-gD – peudorabies virus
    
  • 5x5w – prv-gD + nectin-1
    
  • 1jma – Hhv1gD extracellular domain (mutant) + herpes virus entry mediator (mutant)
    
  • 3sku – Hhv1gD extracellular domain + herpes virus entry mediator
    
  • 3u82, 4myw – Hhv2gD extracellular domain + poliovirus receptor-related protein
    
  • 3w9e – Hhv2gD + antibody
    
  • 6ls9 - bgD – bovine alphaherpesvirus 1
    
  • 6lsa – bgD + nectin-1
    
  • 6sqj - gD – equine alphaherpesvirus 1
    
  • 6tm8 - gD – equine alphaherpesvirus 4