4e7r

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Thrombin in complex with 3-amidinophenylalanine inhibitorThrombin in complex with 3-amidinophenylalanine inhibitor

Structural highlights

4e7r is a 6 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.25Å
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HIRV2_HIRME Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.

See Also

4e7r, resolution 2.25Å

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