2uw2

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Crystal structure of human ribonucleotide reductase subunit R2Crystal structure of human ribonucleotide reductase subunit R2

Structural highlights

2uw2 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2iyh. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RIR2_HUMAN Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2uw2, resolution 2.80Å

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