1s4z
HP1 chromo shadow domain in complex with PXVXL motif of CAF-1HP1 chromo shadow domain in complex with PXVXL motif of CAF-1
Structural highlights
FunctionCBX1_MOUSE Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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