1qyu

Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluDStructure of the catalytic domain of 23S rRNA pseudouridine synthase RluD

Structural highlights

1qyu is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RLUD_ECOLI Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Wrzesinski J, Bakin A, Ofengand J, Lane BG. Isolation and properties of Escherichia coli 23S-RNA pseudouridine 1911, 1915, 1917 synthase (RluD). IUBMB Life. 2000 Jul;50(1):33-7. PMID:11087118 doi:http://dx.doi.org/10.1080/15216540050176566
↑ Leppik M, Peil L, Kipper K, Liiv A, Remme J. Substrate specificity of the pseudouridine synthase RluD in Escherichia coli. FEBS J. 2007 Nov;274(21):5759-66. Epub 2007 Oct 12. PMID:17937767 doi:http://dx.doi.org/10.1111/j.1742-4658.2007.06101.x

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OCA

[1] Wrzesinski J, Bakin A, Ofengand J, Lane BG. Isolation and properties of Escherichia coli 23S-RNA pseudouridine 1911, 1915, 1917 synthase (RluD). IUBMB Life. 2000 Jul;50(1):33-7. PMID:11087118 doi:http://dx.doi.org/10.1080/15216540050176566

[2] Leppik M, Peil L, Kipper K, Liiv A, Remme J. Substrate specificity of the pseudouridine synthase RluD in Escherichia coli. FEBS J. 2007 Nov;274(21):5759-66. Epub 2007 Oct 12. PMID:17937767 doi:http://dx.doi.org/10.1111/j.1742-4658.2007.06101.x

[1]

[2]

1qyu

Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluDStructure of the catalytic domain of 23S rRNA pseudouridine synthase RluD

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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1qyu

Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluDStructure of the catalytic domain of 23S rRNA pseudouridine synthase RluD

Structural highlights

Function

Evolutionary Conservation

See Also

References

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