1gpj

Glutamyl-tRNA Reductase from Methanopyrus kandleriGlutamyl-tRNA Reductase from Methanopyrus kandleri

Structural highlights

1gpj is a 1 chain structure with sequence from Methanopyrus kandleri. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.95Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HEM1_METKA Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). In the absence of NADPH, exhibits substrate esterase activity, leading to the release of glutamate from tRNA.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Moser J, Lorenz S, Hubschwerlen C, Rompf A, Jahn D. Methanopyrus kandleri glutamyl-tRNA reductase. J Biol Chem. 1999 Oct 22;274(43):30679-85. PMID:10521455

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OCA

[1] Moser J, Lorenz S, Hubschwerlen C, Rompf A, Jahn D. Methanopyrus kandleri glutamyl-tRNA reductase. J Biol Chem. 1999 Oct 22;274(43):30679-85. PMID:10521455

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