1g55

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Structure of human DNMT2, an enigmatic DNA methyltransferase homologueStructure of human DNMT2, an enigmatic DNA methyltransferase homologue

Structural highlights

1g55 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TRDMT_HUMAN Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Goll MG, Kirpekar F, Maggert KA, Yoder JA, Hsieh CL, Zhang X, Golic KG, Jacobsen SE, Bestor TH. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science. 2006 Jan 20;311(5759):395-8. PMID:16424344 doi:http://dx.doi.org/311/5759/395

1g55, resolution 1.80Å

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