3vmx

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Crystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channelCrystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channel

Structural highlights

3vmx is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.45Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HVCN1_MOUSE Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis (By similarity).

See Also

3vmx, resolution 1.45Å

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