3mca

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Structure of the Dom34-Hbs1 Complex and implications for its role in No-Go decayStructure of the Dom34-Hbs1 Complex and implications for its role in No-Go decay

Structural highlights

3mca is a 2 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.74Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HBS1_SCHPO Involved in protein translation. Together with dom34, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs (By similarity).[UniProtKB:P32769]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3mca, resolution 2.74Å

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