4do2

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Crystal Structure of the Rop protein mutant D30P/A31G at resolution 1.4 resolution.Crystal Structure of the Rop protein mutant D30P/A31G at resolution 1.4 resolution.

Structural highlights

4do2 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.401Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ROP_ECOLX Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.

See Also

4do2, resolution 1.40Å

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