3ru8

Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 FabStructure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab

Structural highlights

3ru8 is a 3 chain structure with sequence from Homo sapiens, Human immunodeficiency virus, Thermobifida fusca and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.07Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

IGKC_HUMAN Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.^[1]

Function

IGKC_HUMAN

References

↑ Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219

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OCA

[1] Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219

[1]

3ru8

Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 FabStructure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab

Structural highlights

Disease

Function

See Also

References

Contents

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3ru8

Structure of an HIV epitope scaffold in complex with neutralizing antibody b12 FabStructure of an HIV epitope scaffold in complex with neutralizing antibody b12 Fab

Structural highlights

Disease

Function

See Also

References

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