CRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEXCRYSTAL STRUCTURE OF THE MT1-MMP--TIMP-2 COMPLEX

Structural highlights

1bqq is a 2 chain structure with sequence from Bos taurus and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.75Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TIMP2_BOVIN Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1bqq, resolution 2.75Å

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