8vy8

Recombinant alpha bungarotoxin complexed with HAP peptideRecombinant alpha bungarotoxin complexed with HAP peptide

Structural highlights

8vy8 is a 8 chain structure with sequence from Bungarus multicinctus and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

3L21V_BUNMU Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.[UniProtKB:P60615]^[1]

References

↑ Chang L, Lin S, Huang H, Hsiao M. Genetic organization of alpha-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): evidence showing that the production of alpha-bungarotoxin isotoxins is not derived from edited mRNAs. Nucleic Acids Res. 1999 Oct 15;27(20):3970-5. PMID:10497260

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OCA

[1] Chang L, Lin S, Huang H, Hsiao M. Genetic organization of alpha-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): evidence showing that the production of alpha-bungarotoxin isotoxins is not derived from edited mRNAs. Nucleic Acids Res. 1999 Oct 15;27(20):3970-5. PMID:10497260

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8vy8

Recombinant alpha bungarotoxin complexed with HAP peptideRecombinant alpha bungarotoxin complexed with HAP peptide

Structural highlights

Function

References

Contents

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8vy8

Recombinant alpha bungarotoxin complexed with HAP peptideRecombinant alpha bungarotoxin complexed with HAP peptide

Structural highlights

Function

References

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