4ncj

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Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium FlourideCrystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride

Structural highlights

4ncj is a 4 chain structure with sequence from Pyrococcus furiosus DSM 3638. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RAD50_PYRFU Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]

See Also

4ncj, resolution 2.00Å

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