4eyl

Crystal structure of NDM-1 bound to hydrolyzed meropenemCrystal structure of NDM-1 bound to hydrolyzed meropenem

Structural highlights 4eyl is a 2 chain structure with sequence from Klebsiella pneumoniae. The July 2015 RCSB PDB Molecule of the Month feature on New Delhi Metallo-b-Lactamase by David Goodsell is 10.2210/rcsb_pdb/mom_2015_7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.9Å Ligands: , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function BLAN1_KLEPN Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. See Also Beta-lactamase 3D structures

spinqualitylabelsall models 4eyl, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image