3pp2

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Crystal structure of the pleckstrin homology domain of ArhGAP27Crystal structure of the pleckstrin homology domain of ArhGAP27

Structural highlights

3pp2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.421Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RHG27_HUMAN Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).

See Also

3pp2, resolution 1.42Å

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