3dze

Crystal structure of bovine coupling Factor B bound with cadmiumCrystal structure of bovine coupling Factor B bound with cadmium

Structural highlights

3dze is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.15Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ATP5S_BOVIN Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Belogrudov GI. Factor B is essential for ATP synthesis by mitochondria. Arch Biochem Biophys. 2002 Oct 15;406(2):271-4. PMID:12361715
↑ Lee JK, Belogrudov GI, Stroud RM. Crystal structure of bovine mitochondrial factor B at 0.96-A resolution. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13379-84. Epub 2008 Sep 3. PMID:18768789

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OCA

[1] Belogrudov GI. Factor B is essential for ATP synthesis by mitochondria. Arch Biochem Biophys. 2002 Oct 15;406(2):271-4. PMID:12361715

[2] Lee JK, Belogrudov GI, Stroud RM. Crystal structure of bovine mitochondrial factor B at 0.96-A resolution. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13379-84. Epub 2008 Sep 3. PMID:18768789

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