Crystal structure of isolated C2 domain of the methionine uptake transporterCrystal structure of isolated C2 domain of the methionine uptake transporter
Structural highlights
3dhx is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
METN_ECOLI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (Probable). It has also been shown to be involved in formyl-L-methionine transport.[1][2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
↑Gal J, Szvetnik A, Schnell R, Kalman M. The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster. J Bacteriol. 2002 Sep;184(17):4930-2. PMID:12169620
↑Zhang Z, Feige JN, Chang AB, Anderson IJ, Brodianski VM, Vitreschak AG, Gelfand MS, Saier MH Jr. A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch Microbiol. 2003 Aug;180(2):88-100. Epub 2003 Jun 19. PMID:12819857 doi:http://dx.doi.org/10.1007/s00203-003-0561-4
