Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteinsIdentification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins
Structural highlights
1xzo is a 2 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
SCO1_BACSU Neccessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling.[1][2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Mattatall NR, Jazairi J, Hill BC. Characterization of YpmQ, an accessory protein required for the expression of cytochrome c oxidase in Bacillus subtilis. J Biol Chem. 2000 Sep 15;275(37):28802-9. PMID:10837475 doi:http://dx.doi.org/10.1074/jbc.M002741200
↑Ye Q, Imriskova-Sosova I, Hill BC, Jia Z. Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins. Biochemistry. 2005 Mar 1;44(8):2934-42. PMID:15723536 doi:10.1021/bi0480537
