1f2i

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COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNACOCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA

Structural highlights

1f2i is a 12 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.35Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

EGR1_MOUSE Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1f2i, resolution 2.35Å

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