7bn9

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Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3

Structural highlights

7bn9 is a 2 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PBPC_BACSU Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis (Probable). Probably required for both cortical and vegetative peptidoglycan synthesis (Probable). Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin (PubMed:28792086).[1] [2]

See Also

References

  1. ↑ Sassine J, Xu M, Sidiq KR, Emmins R, Errington J, Daniel RA. Functional redundancy of division specific penicillin-binding proteins in Bacillus subtilis. Mol Microbiol. 2017 Oct;106(2):304-318. PMID:28792086 doi:10.1111/mmi.13765
  2. ↑ Buchanan CE, Neyman SL. Correlation of penicillin-binding protein composition with different functions of two membranes in Bacillus subtilis forespores. J Bacteriol. 1986 Feb;165(2):498-503. PMID:3080407 doi:10.1128/jb.165.2.498-503.1986

7bn9, resolution 2.65Å

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