7fi9

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Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2DCrystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D

Structural highlights

7fi9 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.16Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NKG2D_HUMAN Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

See Also

7fi9, resolution 2.16Å

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