4u4m

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Crystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with PyruvateCrystal structure of 0.5M urea unfolded YagE, a KDG aldolase protein in complex with Pyruvate

Structural highlights

4u4m is a 4 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.09Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YAGE_ECOLI Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.

4u4m, resolution 3.09Å

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