3sgi
Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosisCrystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis
Structural highlights
FunctionDNLJ_MYCTU DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] See Also |
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