2zza

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Moritella profunda Dihydrofolate reductase complex with NADP+ and FolateMoritella profunda Dihydrofolate reductase complex with NADP+ and Folate

Structural highlights

2zza is a 2 chain structure with sequence from Moritella profunda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q70YQ6_MORPR Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2zza, resolution 2.00Å

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