2ef1

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Crystal structure of the extracellular domain of human CD38Crystal structure of the extracellular domain of human CD38

Structural highlights

2ef1 is a 2 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2df1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

CD38_HUMAN Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2ef1, resolution 2.40Å

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