8hqc

Structure of a GPCR-G protein in complex with a natural peptide agonistStructure of a GPCR-G protein in complex with a natural peptide agonist

Structural highlights 8hqc is a 6 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.89Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function C5AR1_MOUSE Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB:P21730]

spinqualitylabelsall models 8hqc, resolution 3.89Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image