5ujf

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Crystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound p218 InhibitorCrystal Structure of Mycobacterium tuberculosis Dihydrofolate Reductase Bound p218 Inhibitor

Structural highlights

5ujf is a 1 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DYR_MYCTU Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

See Also

5ujf, resolution 2.30Å

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