4iq8

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Crystal structure of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiaeCrystal structure of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae

Structural highlights

4iq8 is a 1 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.49Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

G3P3_YEAST

Publication Abstract from PubMed

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces cerevisiae, was cloned, expressed, purified and crystallized. The crystals belonged to space group I4(1)22, with unit-cell parameters a = b = 116.13, c = 119.21 A. X-ray diffraction data were collected to a resolution of 2.6 A. The structure was solved by molecular replacement and refinement is in progress.

Preliminary crystallographic analysis of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae.,Liu Q, Wang H, Liu H, Teng M, Li X Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug;68(Pt 8):978-80. doi: , 10.1107/S1744309112028989. Epub 2012 Jul 31. PMID:22869137[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Liu Q, Wang H, Liu H, Teng M, Li X. Preliminary crystallographic analysis of glyceraldehyde-3-phosphate dehydrogenase 3 from Saccharomyces cerevisiae. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug;68(Pt 8):978-80. doi: , 10.1107/S1744309112028989. Epub 2012 Jul 31. PMID:22869137 doi:http://dx.doi.org/10.1107/S1744309112028989

4iq8, resolution 2.49Å

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