Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform AHexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
Structural highlights
3dl2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
UEVLD_HUMAN Possible negative regulator of polyubiquitination.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Kloor M, Bork P, Duwe A, Klaes R, von Knebel Doeberitz M, Ridder R. Identification and characterization of UEV3, a human cDNA with similarities to inactive E2 ubiquitin-conjugating enzymes. Biochim Biophys Acta. 2002 Dec 12;1579(2-3):219-24. PMID:12427560