5e6t

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Crystal structure of bovine norovirus P domainCrystal structure of bovine norovirus P domain

Structural highlights

5e6t is a 2 chain structure with sequence from Norovirus Bo/GIII/B309/2003/BEL. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.27Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

E6Y5B1_9CALI

Publication Abstract from PubMed

We determined a structure of a bovine (genogroup III, GIII) norovirus capsid protruding (P) domain using X-ray crystallography. The bovine P domain was reminiscent of other norovirus genogroups (GI, GII, GIV, and GV), but closely matched the human GI P domain. We also identified a monoclonal antibody that was capable of binding the five different (GI-GV) P domains. Our data suggests that genetically diverse noroviruses still contain common epitopes.

Structural analysis of bovine norovirus protruding domain.,Singh BK, Koromyslova A, Hansman GS Virology. 2015 Nov 17;487:296-301. doi: 10.1016/j.virol.2015.10.022. PMID:26599362[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Singh BK, Koromyslova A, Hansman GS. Structural analysis of bovine norovirus protruding domain. Virology. 2015 Nov 17;487:296-301. doi: 10.1016/j.virol.2015.10.022. PMID:26599362 doi:http://dx.doi.org/10.1016/j.virol.2015.10.022

5e6t, resolution 2.27Å

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