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Crystal structure of bovine norovirus P domainCrystal structure of bovine norovirus P domain
Structural highlights
FunctionPublication Abstract from PubMedWe determined a structure of a bovine (genogroup III, GIII) norovirus capsid protruding (P) domain using X-ray crystallography. The bovine P domain was reminiscent of other norovirus genogroups (GI, GII, GIV, and GV), but closely matched the human GI P domain. We also identified a monoclonal antibody that was capable of binding the five different (GI-GV) P domains. Our data suggests that genetically diverse noroviruses still contain common epitopes. Structural analysis of bovine norovirus protruding domain.,Singh BK, Koromyslova A, Hansman GS Virology. 2015 Nov 17;487:296-301. doi: 10.1016/j.virol.2015.10.022. PMID:26599362[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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