8f60

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anti-BTLA monoclonal antibody r23C8 in complex with BTLAanti-BTLA monoclonal antibody r23C8 in complex with BTLA

Structural highlights

8f60 is a 3 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.64Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BTLA_HUMAN Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.[1]

See Also

References

  1. Watanabe N, Gavrieli M, Sedy JR, Yang J, Fallarino F, Loftin SK, Hurchla MA, Zimmerman N, Sim J, Zang X, Murphy TL, Russell JH, Allison JP, Murphy KM. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat Immunol. 2003 Jul;4(7):670-9. Epub 2003 Jun 8. PMID:12796776 doi:http://dx.doi.org/10.1038/ni944

8f60, resolution 1.64Å

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