Methionine synthase 3D structures

Methionine synthaseMethionine synthase

Updated on 28-June-2023

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• Cobalamin-dependent Methionine synthase
  • 2o2k – hMetH activation domain 926-1265 (mutant) – human
    
  • 1j6r – TmMetH activation domain 1-202 – Thermotoga maritima
    
  • 1q7m, 1q7q, 1q7z, 1q85, 1q8a – TmMetH 1-566
    
  • 5von – TtMetH folate-binding domain 353-648 – Thermus thermophilus
    
  • 4ztx, 4zty – MetH – Neurospora crassa
    
  • 3k13 – MetH pterin-binding domain 353-648 – Bacterioides thetaiotaomicron
    
• Methionine synthase binary complex
  • 4ccz – hMetH homocysteine and folate-binding domain 16-657 + folate derivative
    
  • 1k7y, 1k98, 3bul, 3iv9 – EcMetH activation domain 651-1227 (mutant) + cobalamine – Escherichia coli
    
  • 8g3h – MetH + cobalamine – Thermus filiformis
    
  • 1msk, 6bm5 – EcMetH activation domain + SAM
    
  • 6bm6 – EcMetH activation domain + SAH
    
  • 6bdy – EcMetH activation domain + sinefugin
    
  • 1bmt – EcMetH cobalamine-binding domain 650-895 + cobalamine
    
  • 3bof, 3bol – TmMetH 1-566 + homocysteine
    
  • 5voo, 5vop – TtMetH folate-binding domain + folate derivative
    
• Methionine synthase ternary complex
  • 3iva – EcMetH C-terminal (mutant) + cobalamine + SAH
    
  • 1q8j – TmMetH 1-566 + folate derivative + homocysteine
    
• Cobalamin-independent methionine synthase
  • 1u1u – AtMetH – Arabidopsis thaliana
    
  • 1u1h – AtMetH + Met
    
  • 1u22 – AtMetH + folate derivative
    
  • 1u1j – AtMetH + folate derivative + Met
    
  • 3rpd – MetH 1-354 - Shewanella
    
  • 2nq5, 3l7r, 3t0c – MetH – Streptococcus mutans
    
  • 1t7l – TmMetH 1-566
    
  • 3bq6 – TmMetH 2-734
    
  • 1xr2 – TmMetH 1-566 + folate derivative
    
  • 1xdj, 3bq5 – TmMetH 1-566 + homocysteine
    
  • 1xpg – TmMetH 1-566 + folate derivative
    
  • 3ppc, 3ppf, 3ppg, 3pph – CaMetH (mutant) – Candida albicans<br />
  • 4l5z, 4l64 – CaMetH (mutant) + homocysteine
    
  • 4qqu – CaMetH (mutant) + homocysteine
    
  • 4l61 – CaMetH (mutant) + Met
    
  • 4l6o – CaMetH (mutant) + Gln
    
  • 4l65 – CaMetH (mutant) + folate derivative + Met
    
  • 4l6h – CaMetH (mutant) + methotrexate + homocysteine