Structural and mechanistic basis for allostery in the bacterial chaperonin GroELStructural and mechanistic basis for allostery in the bacterial chaperonin GroEL

Structural highlights

4v43 is a 28 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entries 1j4z and 1kpo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CH60_ECOLI Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]

See Also

4v43, resolution 3.52Å

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OCA