4roj

Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptideCrystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide

Structural highlights 4roj is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function VAV2_HUMAN Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). See Also Vitamin D receptor 3D structures

spinqualitylabelsall models 4roj, resolution 1.95Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image